Analysis of the main comorbidities and delivery routes in pregnant women with COVID-19 in Santa Catarina
Keywords:
COVID-19, Pregnancy, ComorbiditiesAbstract
In December 2019, an unknown etiology disease emerged. After a virus isolation and
molecular analysis, it was possible to identify that the etiological agent was a new
pathogenic human coronavirus that was causing COVID-19. In addition to the
identification of SARS-CoV-2 binding to ACE2 receptors in alveolar cells, it was also verified that it bound to the placenta, so pregnant women were considered a risk group
during the pandemic, if they contracted the new virus. Thus, this new time of change
brought questions about the impact of the disease on pregnancy. Subsequently, new
studies showed that the severity of the disease increased with the types of previous
comorbidities in this population, with risks for both the mother and the newborn. The
studies also showed the delivery routes in these patients, listing possible perinatal
complications and the methods chosen by professionals working in the area in the defined
period of the COVID-19 pandemic.
References
ALZAMORA, M. C. et al. Severe COVID-19 during pregnancy and possible vertical transmission. American Journal of Perinatology, v. 37, n. 8, p. 861–865, 1 jun. 2020.
SUS. Superintendência de Vigilância em Saúde. Secretaria de Estado da Saúde. Governo do Estado de Santa Catarina. Nota de alerta conjunta n° 008/2021/DIVE/SUV - DAPS/SPS. Florianópolis, 2021.
DI TORO, F. et al. Impact of COVID-19 on maternal and neonatal outcomes: a systematic review and meta-analysis. Clinical Microbiology and Infection, v. 27, n. 1, p. 36–46, 2021.
LI, M. et al. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study. PLoS ONE, v. 15, n. 4, p. 1–12, 2020.
MATSUYAMA, S. et al. Enhanced isolation of SARS-CoV-2 by TMPRSS2- expressing cells. Proceedings of the National Academy of Sciences of the United States of America, v. 117, n. 13, p. 7001–7003, 2020.
MENG, L.; HUA, F.; BIAN, Z. Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine. Journal of Dental Research, v. 2019, 2020.
PAPAPANOU, M. et al. Maternal and neonatal characteristics and outcomes of covid19 in pregnancy: An overview of systematic reviews. International Journal of Environmental Research and Public Health, 2 jan. 2021.
TOZATO, C. et al. Cardiopulmonary rehabilitation in post-COVID-19 patients: Case series. Revista Brasileira de Terapia Intensiva, v. 33, n. 1, p. 167–171, 2021.
VILLAR, J. et al. Maternal and neonatal morbidity and mortality among pregnant women with and without COVID-19 infection: The INTERCOVID Multin