Fraturas ósseas: complexidade biológica e avanços terapêuticos com nanotecnologia
Palavras-chave:
Fratura, Formação óssea, NanopartículaResumo
As fraturas ósseas representam um desafio relevante à saúde pública, especialmente em contextos de envelhecimento populacional e crescimento de traumas de alta energia. A reparação óssea é um processo biológico complexo, envolvendo múltiplos tipos celulares, sinalizações moleculares e interações com o microambiente tecidual. Frente às limitações dos métodos tradicionais de tratamento, como enxertos autólogos ou sintéticos, a nanotecnologia surge como alternativa promissora. Este trabalho de revisão discute os mecanismos celulares da osteogênese, as dificuldades enfrentadas nos casos de fraturas complexas e os avanços terapêuticos associados ao uso de nanopartículas bioativas como ferramentas no estímulo à regeneração óssea
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